Introducing ClearUP® Sinus Pain Relief

A drug-free, highly effective microcurrent treatment for the temporary relief of sinus pain associated with allergic rhinitis.

Clinically proven

A clinical study found that 3 out of 4 users achieved sinus pain relief after a single use. 82 percent of users preferred ClearUP to their current treatment.

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Try ClearUP

Experience how ClearUP is different from other sinus treatments. The easy-to-use design empowers people to control their sinus pain symptoms.

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Mechanisms of action:
two principal pathways

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1. Vasoconstriction

Electrical stimulation of sympathetic nerve fibers has been shown to promote release of norepinephrine.

Norepinephrine facilitates smooth muscle contraction around the blood vessels, leading to vasoconstriction.

Vasoconstriction of arterioles and venous vessels, in the context of sinonasal inflammation, results in smaller vessel diameter, relieving pressure on the nerves and reducing resistance to air flow.

Over time, repeated vasoconstriction can reduce edema and extravasation of inflammatory immune cells, contributing to reduced symptom severity.

2. Trigeminal Nerve Stimulation

The trigeminal nerve – the ophthalmic nerve (V1) and maxillary nerve (V2) – is responsible for relaying sensory information to the brain.

Electrical microcurrent delivered in the periorbital regions stimulates subcutaneous fibers of these branches.

Neuromodulation of the trigeminal nerve pathway may alleviate sensations of pain and pressure in very short periods of time.

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